10 North Carolina, overcoming 21.5-point underdog odds in Week 8. Notably, they achieved an unexpected victory against the then-ranked No. Despite these hurdles, the Cavaliers are eyeing their second triumph against a ranked opponent. Presently standing at 2-7 overall and holding a 1-4 record in the ACC, Virginia finds itself in a two-game losing streak, joining a group of four ACC teams with only one or zero wins in conference play this season. Louisville prediction based on the best college football odds. The Louisville Cardinals are the only ranked team in action before the weekend when they host the Virginia Cavaliers on Thursday night, and we offer our best Virginia vs.